Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL673998 | 0.83 | ESR1 (0.54) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7972245 | 0.83 | ESR1 (0.54) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL22980343 | 0.81 | ESR1 (0.52) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL226013 | 0.81 | ESR1 (0.64) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7943477 | 0.77 | TSHR (0.42) | ESR1ESR2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL7937250 | 0.77 | ALOX15 (0.34) | ESR1ESR2CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL7946596 | 0.77 | TSHR (0.61) | ESR1CA2CA1CYP2C9CYP1A2 | |
| SCHEMBL2029120 | 0.77 | ESR1 (0.54) | ESR1ESR2CA2CA1CYP2C9 | |
| SCHEMBL7510606 | 0.76 | ESR1 (0.63) | ESR1ESR2ALDH1A1TP53ALOX15 | |
| SCHEMBL992397 | 0.76 | ESR1 (0.47) | ESR1ESR2CA2CA1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258498-B1 | POLYCARBONATE PROTECTIVE COATING | CANON KABUSHIKI KAISHA (JP) | 2001-07-10 | — | — | US | disclosed |
| US-6143489-A | ELEMENTS HAVING HIGH SHARPNESS AS WELL AS LOW FOG DENSITY AND IMPROVED IMAGE RETENTION UNDER ILLUMINATED LIGHT | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| US-6071687-A | COMPRISING A PHOTOSENSITIVE SILVER HALIDE EMULSION LAYER CONTAINING A NON-PHOTOSENSITIVE ORGANIC SILVER SALT, A REDUCING AGENT AND BINDER; GOOD COVERING POWER AND SILVER TONE, LOW GRAININESS | FUJI PHOTO FILM CO., LTD. (JP) | 2000-06-06 | — | — | US | disclosed |