SCHEMBL7944907

SCHEMBL7944907

COc1c(C2CCCCC2)cc(C(=O)OCCO)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
SLC29A1 Q99808 6/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
LMNA P02545 2/20 0.37
SCN1A P35498 2/20 0.37
SCN2A Q99250 2/20 0.37
SCN3A Q9NY46 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
ABCC4 O15439 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37
MAPK1 P28482 1/20 0.37
SLC6A4 P31645 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7940670 0.87 GAA (0.38) SMN1; SMN2KMT2AMEN1LMNAALDH1A1
SCHEMBL7942538 0.86 THRB (0.39) THRBSLC29A1SMN1; SMN2KMT2AMEN1
SCHEMBL7944751 0.85 THRB (0.39) THRBSLC29A1SMN1; SMN2KMT2AMEN1
SCHEMBL7944853 0.84 TNFRSF1A (0.45) SLC29A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL8430350 0.82 L3MBTL1 (0.43) THRBSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL7794874 0.81 KMT2A (0.42) KMT2AKCNH2PTGDR2TDP1TNFRSF1A
SCHEMBL7941423 0.81 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1
SCHEMBL7942462 0.79 ESR1 (0.41) SLC29A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL7933935 0.78 SLC29A1 (0.39) SLC29A1SMN1; SMN2KMT2AMEN1LMNA
SCHEMBL7944788 0.77 PTGDR2 (0.47) SMN1; SMN2KMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed