Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837657 | 0.81 | ALDH1A1 (0.53) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL1567346 | 0.78 | LMNA (1.00) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL6325724 | 0.78 | LMNA (0.68) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL6325644 | 0.78 | LMNA (0.68) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL333242 | 0.77 | LMNA (0.67) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL6324681 | 0.77 | FFAR1 (0.75) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL6327249 | 0.76 | LMNA (0.76) | LMNAATMMITFTP53NCOA3 | |
| SCHEMBL7829263 | 0.75 | HPGD (0.46) | LMNAATMMAPTALDH1A1POLB | |
| SCHEMBL7818703 | 0.74 | ALDH1A1 (0.64) | LMNAATMTP53NCOA3FFAR1 | |
| SCHEMBL24332395 | 0.73 | RXRA (0.54) | LMNAATMTP53MAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329389-B1 | HETEROCYCLIC AMINES AND DERIVATIVES, SOMATOSTATIN AND ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-11 | — | — | US | disclosed |