Sugi Predict

Sugi Predict / Compounds / SCHEMBL124028

SCHEMBL124028

SCHEMBL124028

CC(C)N1CCN=C1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.46
▸ GAA P10253 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ PTAFR P25105 2/20 0.41
▸ HPGD P15428 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ LMNA P02545 2/20 0.40
▸ THRB P10828 1/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ CA7 P43166 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10365363 0.86 POLB (0.44) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL9207857 0.86 POLB (0.47) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL2898646 0.82 POLB (0.41) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL522530 0.80 CYP19A1 (0.41) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL10046459 0.77 PTAFR (0.42) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL4035735 0.76 NCF1 (0.41) PTAFR
SCHEMBL10046467 0.76 ALDH1A1 (0.42) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL14047408 0.76 TOP2A (0.39) POLBCA1CA2CA4CA7
SCHEMBL122260 0.75 ADORA3 (0.46) POLBGAAALDH1A1RECQLPTAFR
SCHEMBL10046471 0.74 OPRM1 (0.44) POLBGAAALDH1A1RECQLPTAFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5189118-A MIXTURES OF 1-ISOPROPYL-2-ARYL IMIDAZOLE AND 1-ISOPROPYL-2-ARYL IMIDAZOLINE AS EPOXY RESIN CURATIVES TEXACO CHEMICAL COMPANY (US) 1993-02-23 — — US claimed
EP-0501074-A1 Mixtures of 1-isopropyl-2-aryl imidazole and 1-isopropyl-2-aryl imidazoline as epoxy resin curative compositions TEXACO CHEMICAL COMPANY (US) 1992-09-02 — — EP claimed
JP-5078455-A — — None — — JP disclosed
US-10662211-B2 Catalysts and methods for polymer synthesis Saurdi Aramco Technologies Company (SA) 2020-05-26 — — US disclosed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 — — US disclosed
US-9951096-B2 Catalysts and methods for polymer synthesis SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-04-24 — — US disclosed
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-06-29 — — US disclosed
US-20150126502-A1 INHIBITORS OF POLO-LIKE KINASE ELAN PHARM INC (US) 2015-05-07 — — US disclosed
US-8859695-B2 Activator for epoxy resin compositions SIKA TECHNOLOGY AG (CH) 2014-10-14 — — US disclosed
US-20130253094-A1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2013-09-26 — — US disclosed
US-20130231335-A1 INHIBITORS OF POLO-LIKE KINASE ELAN PHARMACEUTICALS, INC. (US) 2013-09-05 — — US disclosed
EP-2274359-B1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2012-03-07 — — EP disclosed
US-20110212942-A1 INHIBITORS OF POLO-LIKE KINASE ELAN PHARMACEUTICALS, INC. 2011-09-01 — — US disclosed
US-20110039109-A1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-02-17 — — US disclosed
EP-2274359-A1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS Sika Technology AG (CH) 2011-01-19 — — EP disclosed
WO-2009133168-A1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2009-11-05 — — WO disclosed
EP-2113525-A1 Activator for epoxy resin composites Sika Technology AG (CH) 2009-11-04 — — EP disclosed
JP-H0578455-A CURING AGENT COMPOSITION FOR EPOXY RESIN AND CURING OF EPOXY RESIN TEXACO CHEM CO 1993-03-30 — — JP disclosed
US-5189118-A MIXTURES OF 1-ISOPROPYL-2-ARYL IMIDAZOLE AND 1-ISOPROPYL-2-ARYL IMIDAZOLINE AS EPOXY RESIN CURATIVES TEXACO CHEMICAL COMPANY (US) 1993-02-23 — — US disclosed
EP-0501074-A1 Mixtures of 1-isopropyl-2-aryl imidazole and 1-isopropyl-2-aryl imidazoline as epoxy resin curative compositions TEXACO CHEMICAL COMPANY (US) 1992-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110212942-A1 INHIBITORS OF POLO-LIKE KINASE PLK1, POLK, POLR2E POLB 9/4885GAA 670/4885ALDH1A1 4226/4885
US-10662211-B2 Catalysts and methods for polymer synthesis PPOX, COASY, SOD1 POLB 121/4885GAA 668/4885ALDH1A1 2255/4885
US-20130231335-A1 INHIBITORS OF POLO-LIKE KINASE POLK, PLK1, POLR2E POLB 9/4885GAA 712/4885ALDH1A1 4256/4885
US-20150126502-A1 INHIBITORS OF POLO-LIKE KINASE POLK, PLK1, POLR2E POLB 9/4885GAA 712/4885ALDH1A1 4256/4885
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 POLB 121/4885GAA 668/4885ALDH1A1 2255/4885
US-20110039109-A1 ACTIVATOR FOR EPOXY RESIN COMPOSITIONS AHSA1, HSF1, HSPA1A POLB 3152/4885GAA 665/4885ALDH1A1 1533/4885
US-20170183369-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 POLB 121/4885GAA 668/4885ALDH1A1 2255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.