SCHEMBL7945130

SCHEMBL7945130

C=Cc1ccccc1-c1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.52
HDAC4 P56524 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
BACE1 P56817 2/20 0.46
ACHE P22303 1/20 0.43
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
ESR2 Q92731 2/20 0.42
ESR1 P03372 1/20 0.42
ALOX5 P09917 1/20 0.41
DHFR P00374 1/20 0.41
KDM4E B2RXH2 2/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
CCNC P24863 2/20 0.39
CDK8 P49336 2/20 0.39
MAOB P27338 1/20 0.38
ADORA2A P29274 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30618853 1.00 GSTP1 (0.52) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL8758212 0.94 GSTP1 (0.46) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL8758630 0.86 ALDH1A1 (0.44) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL8758617 0.84 ALDH1A1 (0.45) GSTP1BACE1ESR2ESR1ALDH1A1
SCHEMBL3147571 0.81 ALDH1A1 (0.39) GSTP1BACE1ACHEKDM4EALDH1A1
SCHEMBL9306706 0.81 ESR2 (0.53) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL19558310 0.81 CYP2A6 (0.50) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL2467050 0.81 ALDH1A1 (0.48) ALDH1A1MEN1HPGDMAPK1KMT2A
SCHEMBL868484 0.81 GSTP1 (0.57) GSTP1HDAC4HDAC2HDAC8BACE1
SCHEMBL31406989 0.81 GSTP1 (0.57) GSTP1HDAC4HDAC2HDAC8BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP disclosed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO disclosed
WO-2015023001-A1 NOVEL ORGANOPOLYSILOXANE, SURFACE TREATMENT AGENT COMPRISING THE SAME, RESIN COMPOSITION COMPRISING THE SAME, AND GELATINOUS PRODUCT OR CURED PRODUCT THEREOF DOW CORNING TORAY CO., LTD. (JP) 2015-02-19 WO disclosed
US-6169154-B1 MACROMONOMER DERIVABLE FROM ETHYLENE SINGLY OR DERIVABLE FROM ETHYLENE AND ANOTHER OLEFIN, THE MACROMONOMER HAVING A BRANCH OTHER THAN THE BRANCH DERIVED FROM THE OTHER OLEFIN; CAN BE HYDROGENATED TO PROVIDE A WAX IDEMITSU KOSAN CO., LTD. (JP) 2001-01-02 US disclosed
EP-0727446-B1 BRANCHED ETHYLENE MACROMONOMER AND POLYMER PRODUCED THEREFROM IDEMITSU KOSAN CO (JP) 2000-09-13 EP disclosed
US-5955557-A Branched ethylenic macromonomer and its polymer IDEMITSU KOSAN CO., LTD. (JP) 1999-09-21 US disclosed
EP-0570932-B1 Styrenic block copolymer and process for producing same IDEMITSU KOSAN CO (JP) 1997-07-23 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5554695-A Styrenic copolymer and process for producing same IDEMITSU KOSAN CO. LTD. (JP) 1996-09-10 US disclosed
US-5391626-A Syndiotactic, high performance, compatibility and adhesiveness; molding materials IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0444210-A1 ARYLSTYRENE POLYMER AND COPOLYMER AND PROCESS FOR PREPARING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-09-04 EP disclosed