SCHEMBL7945245

SCHEMBL7945245

CCC([SiH3])=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.43
AKR1C3 P42330 1/20 0.43
NR1I2 O75469 1/20 0.43
LMNA P02545 2/20 0.42
RECQL P46063 1/20 0.41
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
FBP1 P09467 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59713 0.76 KDM1A (0.48) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL7855199 0.76 KDM1A (0.48) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL8072809 0.75 ALDH1A1 (0.48) KDM1AALDH1A1TSHRAKR1C3LMNA
SCHEMBL110774 0.74 TSHR (0.50) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL5027068 0.74 TSHR (0.50) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL598599 0.74 TSHR (0.50) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL4911765 0.74 ALDH1A1 (0.41) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL140742 0.73 ALDH1A1 (0.54) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL5598300 0.73 KDM1A (0.50) KDM1AMEN1KMT2AALDH1A1TSHR
SCHEMBL9310823 0.73 KDM1A (0.46) KDM1AMEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001046276-A1 METALLOCENE CATALYSTS HAVING MULTI-NUCLEAR CONSTRAINED GEOMETRY AND ETHYLENE/AROMATIC VINYL COMPOUND CO-POLYMERS PREPARED BY USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-06-28 WO disclosed