Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148328 | 1.00 | EPHX1 (0.54) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL3116167 | 0.97 | EPHX1 (0.50) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL3855877 | 0.91 | KMT2A (0.44) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL11974545 | 0.89 | EPHX1 (0.56) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL502374 | 0.87 | EPHX1 (0.48) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL9298439 | 0.86 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL3846912 | 0.85 | HPGD (0.47) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL12467258 | 0.85 | EPHX1 (0.47) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL8397024 | 0.85 | EPHX1 (0.47) | EPHX1HPGDKMT2AEPHX2ALOX5 | |
| SCHEMBL9798709 | 0.85 | EPHX1 (0.52) | EPHX1HPGDKMT2AEPHX2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252118-B1 | REACTING A KETONE HAVING A BETA HYDROGEN WITH AN OLEFIN CATALYZED BY A TRANSITION METAL CATALYST COMPOUND WITH THE AID OF A 2-AMINOPYRIDINE DERIVATIVE | Jun, Chul Ho (KR) | 2001-06-26 | — | — | US | disclosed |