Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.37 |
| ▸ | ADH1C | P00326 | 1/20 | 0.37 |
| ▸ | ADH1A | P07327 | 1/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | ADH7 | P40394 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662692 | 1.00 | HPGD (0.47) | HPGDEPHX1KMT2ATDP1CYP1A2 | |
| SCHEMBL327378 | 0.98 | KMT2A (0.43) | HPGDEPHX1KMT2ATDP1CYP1A2 | |
| SCHEMBL14751461 | 0.93 | — | — | |
| SCHEMBL8106988 | 0.89 | HPGD (0.42) | HPGDEPHX1KMT2ATDP1CYP1A2 | |
| SCHEMBL8618756 | 0.87 | — | — | |
| Thiophene SCHEMBL27537280 | 0.85 | EPHX2 (0.38) | HPGDEPHX1KMT2ATDP1EPHX2 | |
| SCHEMBL7945281 | 0.85 | EPHX1 (0.54) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL1148328 | 0.85 | EPHX1 (0.54) | HPGDEPHX1KMT2AEPHX2ALOX5 | |
| SCHEMBL19867672 | 0.85 | KMT2A (0.38) | HPGDEPHX1KMT2ATDP1EPHX2 | |
| Thiophene SCHEMBL27503885 | 0.82 | EPHX2 (0.36) | HPGDEPHX1KMT2ATDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731725-A | Improved polyolefin composition and preparation method thereof | IND TECH RES INST | 2012-10-17 | — | — | CN | claimed |
| CN-110172274-B | Quantum dot ink and electroluminescent device | 苏州星烁纳米科技有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-110172274-A | Quantum dot ink and electroluminescent device | 苏州星烁纳米科技有限公司 | 2019-08-27 | — | — | CN | disclosed |
| US-9867911-B2 | Rapamycin 40-O-cyclic hydrocarbon esters, compositions and methods | BIOTRONIK AG (CH) | 2018-01-16 | — | — | US | disclosed |
| EP-2693882-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK SHARP & DOHME (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20170021065-A1 | Rapamycin 40-O-Cyclic Hydrocarbon Esters, Compositions and Methods | BIOTRONIK AG (CH) | 2017-01-26 | — | — | US | disclosed |
| EP-1489459-B1 | Positive resist composition and method of forming pattern using the same | FUJIFILM CORP (JP) | 2015-10-14 | — | — | EP | disclosed |
| WO-2015117196-A1 | ANTIBACTERIAL AGENTS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-08-13 | — | — | WO | disclosed |
| US-8841331-B2 | Inhibitors of human immunodeficiency virus replication | GILEAD SCIENCES, INC. (US) | 2014-09-23 | — | — | US | disclosed |
| WO-2013066991-A1 | CRYSTALLINE SOLVATES OF NUCLEOSIDE PHOSPHOROAMIDATES, THEIR STEREOSELECTIVE PREPARATION, NOVEL INTERMEDIATES THEREOF, AND THEIR USE IN THE TREATMENT OF VIRAL DISEASE | INHIBITEX, INC. (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20090123423-A1 | HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS SERINE PROTEASE INHIBITOR | ENANTA PHARMACEUTICALS, INC. | 2009-05-14 | — | — | US | disclosed |
| US-7504391-B2 | Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders | SCHERING CORPORATION (US) | 2009-03-17 | — | — | US | disclosed |
| WO-2009033183-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF HCV AND CONDITIONS ASSOCIATED WITH CD81 BINDING | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2009-03-12 | — | — | WO | disclosed |
| US-20090048297-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS (US) | 2009-02-19 | — | — | US | disclosed |
| US-20080274082-A1 | OXIMYL HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS PROTEASE INHIBITOR | ENANTA PHARMACEUTICALS, INC. | 2008-11-06 | — | — | US | disclosed |
| CN-100343371-C | Heavy fuel oil additive containing benzopyran multi-hydroxy metal compound | CAI KEER (CN) | 2007-10-17 | — | — | CN | disclosed |
| CN-1763158-A | Heavy fuel oil additive containing benzopyran multi-hydroxy metal compound | CAI KEER (CN) | 2006-04-26 | — | — | CN | disclosed |
| US-4370323-A | 2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4067886-A | REACTING KETONES AND KETALS WITH HALOGEN | LEVER BROTHERS COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3956316-A | PROGESTATIONAL AND SALT-RETAINING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080274082-A1 | OXIMYL HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS PROTEASE INHIBITOR | HPN, HCCS, SPINT2 | HPGD 174/4885EPHX1 180/4885KMT2A 1288/4885 |
| US-20090048297-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | VIP, ZC3HAV1, CCL5 | HPGD 4148/4885EPHX1 3367/4885KMT2A 3426/4885 |
| US-20090123423-A1 | HYDROXYAMIC ANALOGS AS HEPATITIS C VIRUS SERINE PROTEASE INHIBITOR | HPN, PRSS1, SERPINB1 | HPGD 237/4885EPHX1 412/4885KMT2A 2252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.