Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351418 | 0.85 | PNMT (0.42) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL6449301 | 0.75 | PNMT (0.39) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL7641521 | 0.74 | PNMT (0.44) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL6446049 | 0.73 | PNMT (0.40) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL61104 | 0.72 | PNMT (0.44) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL7579424 | 0.71 | PNMT (0.41) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL1130438 | 0.71 | PNMT (0.42) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL7580948 | 0.71 | PNMT (0.38) | PNMTDRD2DRD4NPC1RAB9A | |
| SCHEMBL1978363 | 0.71 | PNMT (0.32) | PNMTNPC1RAB9A | |
| SCHEMBL7116325 | 0.70 | PNMT (0.31) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248912-B1 | OF TRANSITION METALS HAVING A TETRAHYDROINDENYL LIGAND BONDED IN THE 2-POSITION | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-19 | — | — | US | disclosed |