Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446049 | 0.87 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL5351418 | 0.85 | PNMT (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7641521 | 0.79 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7579424 | 0.76 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7580948 | 0.76 | PNMT (0.38) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7945303 | 0.75 | PTGS2 (0.35) | PNMTNPC1RAB9ADRD2DRD4 | |
| SCHEMBL648530 | 0.74 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL61104 | 0.74 | PNMT (0.44) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7197599 | 0.74 | PNMT (0.39) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL7580052 | 0.74 | PNMT (0.37) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6841634-B1 | Modified supported catalysts for the polymerization of olefins | BOREALIS TECHNOLOGY OY (FI) | 2005-01-11 | — | — | US | disclosed |
| US-6664352-B1 | Impregnating porous particulate support in mechanically fluidized state with catalyst material in mixer having horizontal axis counter-rotating interlocking mixing paddles | BOREALIS TECHNOLOGY OY (FI) | 2003-12-16 | — | — | US | disclosed |
| US-20030078340-A1 | Impregnating a mechanically fluidized porous particulate support material with a catalyst and polymerizing monomer(s) to produce polymer; heating mixture antioxidants, ultraviolet radiation stabilizer, diluent and metal stearate; depositing | BOREALIS TECHNOLOGY OY (FI) | 2003-04-24 | — | — | US | disclosed |
| US-5945367-A | Metallocenes with silyl-substituted bridges and their use for olefin polymerization | BOREALIS AG (AT) | 1999-08-31 | — | — | US | disclosed |