Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17956756 | 0.87 | GAA (0.71) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL25517519 | 0.86 | HPGD (0.63) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL31388324 | 0.85 | HPGD (0.80) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL3822985 | 0.85 | HPGD (0.80) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL6816152 | 0.84 | KMT2A (0.71) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL7945596 | 0.83 | SMN1; SMN2 (0.76) | ALDH1A1MAPTL3MBTL1HPGDGAA | |
| SCHEMBL11895728 | 0.82 | RAB9A (0.76) | ALDH1A1MAPTMAPK1L3MBTL1HPGD | |
| SCHEMBL13299603 | 0.80 | HPGD (0.68) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL28401848 | 0.79 | ALDH1A1 (0.73) | ALDH1A1MAPTMAPK1HPGDGAA | |
| SCHEMBL458174 | 0.79 | HPGD (0.66) | ALDH1A1MAPTHPGDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |