Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644422 | 0.77 | ATR (0.43) | MEN1KMT2AALDH1A1MAPTCYP11B1 | |
| SCHEMBL764319 | 0.77 | CYP11B1 (0.56) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15599290 | 0.77 | ABL1 (0.43) | CYP1A2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL12248385 | 0.77 | CYP11B1 (0.40) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14438064 | 0.74 | HPGDS (0.42) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12301396 | 0.73 | CYP11B1 (0.40) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL24654518 | 0.72 | CYP11B1 (0.45) | CYP1A2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15784437 | 0.71 | HPGDS (0.46) | MEN1KMT2ACYP3A4MAPK1 | |
| SCHEMBL10000240 | 0.71 | KDM1A (0.47) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL2716273 | 0.71 | RAB9A (0.48) | MEN1KMT2AALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010047372-A1 | 2-AMINOPYRIDIN-4-ONE AND 2-AMINOPYRIDINE DERIVATIVE BOTH HAVING BACE1-INHIBITING ACTIVITY | 塩野義製薬株式会社 (JP) | 2010-04-29 | — | — | WO | disclosed |