Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | ABL2 | P42684 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620418 | 0.92 | NPC1 (0.41) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL14669320 | 0.92 | NPC1 (0.41) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7959056 | 0.90 | KMT2A (0.45) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7945652 | 0.89 | KDM4E (0.43) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL7952123 | 0.88 | HRH4 (0.44) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL19884901 | 0.87 | AKR1C3 (0.46) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6517282 | 0.84 | ADH1A (0.61) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL6517278 | 0.84 | ADH1A (0.61) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL30852737 | 0.83 | P4HB (0.51) | ADH1AKITFLT1FLT4KDR | |
| SCHEMBL19057483 | 0.83 | P4HB (0.51) | ADH1AKITFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |