Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959056 | 0.94 | KMT2A (0.45) | NPC1RAB9AHRH4MEN1KMT2A | |
| SCHEMBL7945647 | 0.89 | ADH1A (0.45) | KDM4ENPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL20991116 | 0.88 | HRH4 (0.47) | KDM4ENPC1RAB9AALDH1A1HRH4 | |
| SCHEMBL6517364 | 0.86 | ADH1A (0.53) | KDM4ENPC1RAB9AHRH4AKR1C3 | |
| SCHEMBL6517359 | 0.86 | ADH1A (0.53) | KDM4ENPC1RAB9AHRH4AKR1C3 | |
| SCHEMBL14669320 | 0.85 | NPC1 (0.41) | KDM4ENPC1RAB9ALMNAAKR1C3 | |
| SCHEMBL6620418 | 0.85 | NPC1 (0.41) | KDM4ENPC1RAB9ALMNAAKR1C3 | |
| SCHEMBL7952123 | 0.85 | HRH4 (0.44) | NPC1RAB9AHRH4MEN1KMT2A | |
| SCHEMBL5864982 | 0.83 | DRD2 (0.44) | KDM4EHRH4AKR1C3MEN1KMT2A | |
| SCHEMBL30360049 | 0.83 | P4HB (0.51) | KDM4ERAB9AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |