Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13530212 | 0.88 | KDM4E (0.62) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL6896687 | 0.88 | ADRB1 (0.58) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL14625616 | 0.86 | TP53 (0.72) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL9698406 | 0.83 | ADRB1 (0.54) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL19101645 | 0.82 | ADRB1 (0.52) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL22606711 | 0.80 | ADRB1 (0.61) | TP53ADRB1DNMT1HTTSMN1; SMN2 | |
| SCHEMBL23865500 | 0.80 | ADRB1 (0.60) | TP53ADRB1DNMT1HTTSMN1; SMN2 | |
| SCHEMBL29619496 | 0.79 | FBP1 (0.56) | FBP1ATIC | |
| SCHEMBL21888115 | 0.78 | ATIC (0.51) | TP53KDM4ETDP1MAPTADRB1 | |
| SCHEMBL6380096 | 0.78 | ADRB1 (0.53) | TP53ADRB1DNMT1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312892-B1 | A METHOD FOR DETECTING SINGLE BASE CHANGES, INSERTIONS, DELETIONS OR TRANSLOCATION OF NUCLEOTIDE SEQUENCES USING LIGASE DETECTION REACTION; FOR CANCER DETECTION | CORNELL RESEARCH FOUNDATION, INC. | 2001-11-06 | — | — | US | claimed |
| EP-0956359-A1 | HIGH FIDELITY DETECTION OF NUCLEIC ACID DIFFERENCES BY LIGASE DETECTION REACTION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-11-17 | — | — | EP | claimed |
| WO-1998003673-A1 | HIGH FIDELITY DETECTION OF NUCLEIC ACID DIFFERENCES BY LIGASE DETECTION REACTION | CORNELL RESEARCH FOUNDATION, INC. (US) | 1998-01-29 | — | — | WO | claimed |
| EP-4154913-A1 | CONJUGATES OF GLUCAGON AND AMPK ACTIVATORS | Københavns Universitet (DK) | 2023-03-29 | — | — | EP | disclosed |