Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694584 | 0.82 | FDPS (0.74) | FDPSBCHEACHEALDH1A1LMNA | |
| SCHEMBL7844422 | 0.81 | TUBB1 (0.57) | FDPSPDCD1CD274TUBB1ALDH1A1 | |
| SCHEMBL8772739 | 0.81 | HTR1A (0.50) | FDPSPDCD1CD274TUBB1ALDH1A1 | |
| SCHEMBL7955166 | 0.80 | FYN (0.47) | FYNACHESCN1ASCN2ASCN3A | |
| SCHEMBL4036416 | 0.80 | FYN (0.53) | FYNACHESCN1ASCN2ASCN3A | |
| SCHEMBL22301646 | 0.80 | FDPS (0.51) | FDPSPDCD1CD274TUBB1ALDH1A1 | |
| SCHEMBL96635 | 0.79 | ALDH1A1 (0.59) | FDPSPDCD1CD274ACHETUBB1 | |
| SCHEMBL16619850 | 0.79 | ALDH1A1 (0.59) | FDPSPDCD1CD274ACHETUBB1 | |
| SCHEMBL7568496 | 0.78 | TUBB1 (0.51) | FDPSTUBB1ALDH1A1MAPK1TUBB4A | |
| SCHEMBL7457620 | 0.78 | TUBB1 (0.55) | FDPSPDCD1CD274TUBB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-1997037985-A1 | NONPEPTIDE ENDOTHELIN ANTAGONISTS WITH INCREASED WATER SOLUBILITY | WARNER-LAMBERT COMPANY (US) | 1997-10-16 | — | — | WO | disclosed |