Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871439 | 0.91 | LIPG (0.43) | L3MBTL1MAPTTHRBRXFP1ALDH1A1 | |
| SCHEMBL5872204 | 0.87 | MAPT (0.53) | L3MBTL1MAPTTHRBRXFP1ALDH1A1 | |
| SCHEMBL5871960 | 0.85 | CNR1 (0.45) | MAPTTHRBRXFP1TP53 | |
| SCHEMBL5872307 | 0.79 | CCNA2 (0.39) | MAPTRXFP1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5872030 | 0.78 | PDE4D (0.43) | L3MBTL1MAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL7959767 | 0.77 | KMT2A (0.41) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7945856 | 0.77 | HDAC1 (0.48) | MAPTALDH1A1SMN1; SMN2TP53LMNA | |
| SCHEMBL5871920 | 0.76 | FEN1 (0.45) | ALDH1A1TSHRHTT | |
| SCHEMBL5872145 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL5871709 | 0.70 | FEN1 (0.50) | L3MBTL1MAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |