Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871960 | 0.88 | CNR1 (0.45) | HDAC1HDAC11HDAC8HDAC6MAPT | |
| SCHEMBL5872030 | 0.87 | PDE4D (0.43) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5872307 | 0.85 | CCNA2 (0.39) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5871920 | 0.81 | FEN1 (0.45) | ALDH1A1KDM4EPDE4APDE4BPDE4C | |
| SCHEMBL5872204 | 0.79 | MAPT (0.53) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL5871709 | 0.77 | FEN1 (0.50) | MAPTALDH1A1KDM4EPDE4APDE4B | |
| SCHEMBL5871439 | 0.77 | LIPG (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7945833 | 0.77 | L3MBTL1 (0.51) | MAPTTP53ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7954338 | 0.73 | PTGDR2 (0.41) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5872145 | 0.71 | ALDH1A1 (0.41) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |