Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | RARG | P13631 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5735473 | 0.74 | RARB (0.41) | RARBRARGRARAGABRA1GABRG2 | |
| SCHEMBL7937173 | 0.73 | GABRA1 (0.42) | GABRA1GABRB2HSPA9 | |
| SCHEMBL3300659 | 0.72 | RARB (0.55) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL5736955 | 0.70 | RARB (0.33) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8558172 | 0.69 | RARB (0.40) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9006905 | 0.67 | AKR1B1 (0.32) | RARBRARGRARAGABRA1GABRG2 | |
| SCHEMBL8616759 | 0.66 | RARB (0.42) | RARBRARGRARAGABRA1GABRG2 | |
| SCHEMBL6664854 | 0.66 | RARB (0.61) | RARBRARGRARAGABRA1GABRG2 | |
| SCHEMBL4373673 | 0.66 | RARB (0.58) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6575676 | 0.65 | RARB (0.39) | RARBRARGRARAGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252090-B1 | Compounds having activity as inhibitors of cytochrome P450RAI | ALLERGAN SALES, INC. | 2001-06-26 | — | — | US | disclosed |