SCHEMBL7946282

SCHEMBL7946282

CCn1ncc(C(=O)c2ccc(S(C)(=O)=O)c(-c3ccc(OC)c(OC)c3)c2C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
PDE4B Q07343 2/20 0.35
KMT2A Q03164 2/20 0.35
CA9 Q16790 1/20 0.35
GLA P06280 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949498 0.92 PTGS2 (0.38) MAPTALDH1A1RAB9ALMNA
SCHEMBL7939695 0.89 MAPK1 (0.37) MAPTKDM4EALDH1A1PDE4BKMT2A
SCHEMBL7946251 0.86 RAB9A (0.36) MAPTKDM4EALDH1A1CA9NPC1
SCHEMBL7946227 0.86 PDE4B (0.36) MAPTKDM4EALDH1A1PDE4BKMT2A
SCHEMBL7947420 0.85 PTGS2 (0.35) ALDH1A1NPC1RAB9AHTTLMNA
SCHEMBL7939860 0.84 SMN1; SMN2 (0.35) ALDH1A1KMT2ANPC1RAB9AHTT
SCHEMBL7951321 0.84 PTGS2 (0.37) ALDH1A1HTT
SCHEMBL7946284 0.84 LMNA (0.34) MAPTKDM4EALDH1A1KMT2ACA9
SCHEMBL7946692 0.84 SMN1; SMN2 (0.37) ALDH1A1KMT2ARAB9AHTTLMNA
SCHEMBL7939787 0.84 PTGS2 (0.38) KDM4EALDH1A1NPC1RAB9AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265606-B1 TO CONTROL A BROAD SPECTRUM OF UNDESIRABLE VEGETATION, ARE SELECTIVE TO MAJOR CROPS, HAVE DESIRABLE ENVIRONMENTAL PROFILES, DOW AGROSCIENCES LLC 2001-07-24 US disclosed
US-6010981-A 1-alkyl-4-benzoyl-5-hydroxypyrazole compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-01-04 US disclosed