Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459033 | 0.86 | RAB9A (0.58) | RAB9AHTTGAAALDH1A1MAPT | |
| SCHEMBL3411267 | 0.86 | RAB9A (0.60) | RAB9AHTTGAAALDH1A1MAPT | |
| SCHEMBL13929792 | 0.82 | L3MBTL1 (0.60) | RAB9AHTTGAAALDH1A1MAPT | |
| SCHEMBL3712764 | 0.82 | MEN1 (0.60) | RAB9AALDH1A1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL42327 | 0.81 | MEN1 (0.59) | RAB9AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL19237513 | 0.77 | RAB9A (0.49) | RAB9AHTTGAAALDH1A1MAPT | |
| SCHEMBL28654555 | 0.76 | RAB9A (0.66) | RAB9AHTTGAAALDH1A1MAPT | |
| SCHEMBL28648496 | 0.76 | ALDH1A1 (0.74) | RAB9AHTTALDH1A1MAPTKMT2A | |
| SCHEMBL16763126 | 0.76 | MAOB (0.63) | RAB9AGAAALDH1A1MAPTNPC1 | |
| SCHEMBL3722770 | 0.76 | MAPK1 (0.59) | RAB9AHTTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013142328-A1 | SMALL MOLECULE ANTAGONISTS OF PF4 CONTAINING ULTRA LARGE COMPLEXES | THE TRUSTEES OF THE UNIVERSITY OF PENSYLVANIA (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013142328-A1 | SMALL MOLECULE ANTAGONISTS OF PF4 CONTAINING ULTRA LARGE COMPLEXES | THE TRUSTEES OF THE UNIVERSITY OF PENSYLVANIA (US) | 2013-09-26 | — | — | WO | disclosed |
| US-6262084-B1 | Compounds that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION | 2001-07-17 | — | — | US | disclosed |