Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946384 | 0.87 | LMNA (0.57) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL7552121 | 0.86 | LMNA (0.54) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL17978582 | 0.81 | CRHBP (0.69) | LMNAPOLBMAPTGAACYP2C9 | |
| SCHEMBL7923440 | 0.77 | CA12 (0.50) | LMNAKMT2AMAPTMEN1GAA | |
| SCHEMBL11325469 | 0.77 | LMNA (0.83) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL8684046 | 0.76 | CA12 (0.50) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL7487873 | 0.76 | POLB (0.50) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL8682320 | 0.75 | POLB (0.47) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL27180913 | 0.74 | POLB (0.68) | LMNAPOLBKMT2AMAPTMEN1 | |
| SCHEMBL30561863 | 0.72 | ALDH1A1 (0.66) | LMNAKMT2AMAPTSMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262113-B1 | HYDROXY- OR MERCAPTO-PHENYLUREAS | SMITHKLINE BEECHAM CORPORATION | 2001-07-17 | — | — | US | disclosed |