SCHEMBL7946403

SCHEMBL7946403

CCCCCC(=O)OC(OOC(C)(C)C)C(CC)CCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
MAPK1 P28482 3/20 0.42
MAPT P10636 2/20 0.42
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PRKCA P17252 4/20 0.38
PRKCE Q02156 1/20 0.38
PRKCQ Q04759 1/20 0.38
PRKCD Q05655 1/20 0.38
CYP1A2 P05177 2/20 0.36
DGKA P23743 1/20 0.36
EPHX2 P34913 1/20 0.36
MEN1 O00255 1/20 0.35
GMNN O75496 1/20 0.35
HSP90AA1 P07900 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38656927 0.88 LMNA (0.41) LMNAMAPK1MAPTTSHRALDH1A1
SCHEMBL6436927 0.87 LMNA (0.40) LMNAMAPK1MAPTTSHRALDH1A1
SCHEMBL165678 0.85 CA2 (0.38) MAPK1TSHRCYP3A4ATMTDP1
SCHEMBL165679 0.84 CA2 (0.40) MAPK1TSHRCYP3A4ATMTDP1
SCHEMBL28970417 0.82 CA2 (0.35) MAPK1
SCHEMBL28187629 0.78 CA2 (0.32) MAPK1
SCHEMBL28959718 0.78 ATM (0.32) TSHRCYP3A4ATMTDP1NPSR1
SCHEMBL29027445 0.76 CA2 (0.33) MAPK1
SCHEMBL94108 0.76 LMNA (0.56) LMNAMAPK1MAPTTSHRALDH1A1
SCHEMBL114018 0.74 CA2 (0.36) MAPK1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3682866-B1 METHOD FOR PREPARING OIL-IN-WATER TYPE EMULSION COMPOSITION, AND COSMETIC MATERIAL SHINETSU CHEMICAL CO (JP) 2024-09-18 EP disclosed
US-11298299-B2 Method for preparing oil-in-water type emulsion composition, and cosmetic material SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-04-12 US disclosed
US-20210154105-A1 METHOD FOR PREPARING OIL-IN-WATER TYPE EMULSION COMPOSITION, AND COSMETIC MATERIAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-05-27 US disclosed
EP-3682866-A1 METHOD FOR PREPARING OIL-IN-WATER TYPE EMULSION COMPOSITION, AND COSMETIC MATERIAL Shin-Etsu Chemical Co., Ltd. (JP) 2020-07-22 EP disclosed
US-9403925-B2 Curable composition and cured article ADEKA CORPORATION (JP) 2016-08-02 US disclosed
US-20140187715-A1 CURABLE COMPOSITION AND CURED ARTICLE ADEKA CORPORATION (JP) 2014-07-03 US disclosed
EP-2749581-A1 CURABLE COMPOSITION AND CURED ARTICLE Adeka Corporation (JP) 2014-07-02 EP disclosed
US-6313249-B1 FREE RADICAL ADDITION COPOLYMERIZATION OF ORGANOPOLYSILOXANE WITH POLYMERIZABLE END GROUP AND ETHYLENICALLY UNSATURATED MONOMER; HEATING, CATALYSIS; PRESSURIZATION AND HYDROGENATION; CATALYST REMOVAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-06 US disclosed
EP-0588560-B1 A curable resin composition, a coating composition and a process for forming a coating film NIPPON PAINT CO LTD (JP) 1998-06-17 EP disclosed
EP-0628613-B1 Aqueous coating composition NIPPON PAINT CO LTD (JP) 1998-05-06 EP disclosed
US-5700862-A FORMS FILM HAVING IMPROVED APPEARANCE, HIGH WORKABILITY, FREE FROM SAGGING AND UNEVENNESS NIPPON PAINT CO., LTD. (JP) 1997-12-23 US disclosed
US-5462770-A Curing paint layers comprising polysiloxanes with hydroxyl, carboxyl groups and acrylic polymers with epoxy, hydroxy and anhydride groups NIPPON PAINT CO., LTD. (JP) 1995-10-31 US disclosed
US-5432233-A A-hydroxyl- and carboxyl-containing silicone polymer from hydroxyl silicone polymer and anhydride, B-carboxylate polymer from hydroxyl compound and polymer of unsaturated anhydride, c-hydroxyl and epoxy polymer by copolymerizing NIPPON PAINT CO., LTD. (JP) 1995-07-11 US disclosed
EP-0628613-A2 Aqueous coating composition NIPPON PAINT CO., LTD. (JP) 1994-12-14 EP disclosed
EP-0588560-A2 A curable resin composition, a coating composition and a process for forming a coating film Nippon Paint Co., Ltd. (JP) 1994-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210154105-A1 METHOD FOR PREPARING OIL-IN-WATER TYPE EMULSION COMPOSITION, AND COSMETIC MATERIAL LIPA, POLB, DAGLB LMNA 238/4885MAPK1 3522/4885MAPT 4111/4885
US-11298299-B2 Method for preparing oil-in-water type emulsion composition, and cosmetic material LIPA, POLB, DAGLB LMNA 238/4885MAPK1 3522/4885MAPT 4111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.