Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947531 | 0.82 | PDE4B (0.39) | PRMT5WDR77 | |
| SCHEMBL2217843 | 0.82 | PRMT5 (0.37) | PRMT5WDR77 | |
| SCHEMBL12513248 | 0.76 | CA12 (0.39) | — | |
| SCHEMBL2170670 | 0.72 | PDE4B (0.45) | PRMT5WDR77 | |
| SCHEMBL2216527 | 0.67 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL12334179 | 0.67 | PDE4B (0.31) | — | |
| SCHEMBL2170946 | 0.65 | F11 (0.36) | — | |
| SCHEMBL2170930 | 0.65 | PARP10 (0.47) | — | |
| SCHEMBL2232198 | 0.61 | ALOX15 (0.35) | — | |
| SCHEMBL29963852 | 0.61 | PRMT5 (0.38) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035745-A1 | HETEROCYCLIC BIARYL DERIVATIVE, AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2010-04-01 | — | — | WO | disclosed |