Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21171359 | 0.89 | MAPT (0.76) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6057244 | 0.89 | TDP1 (0.69) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31137861 | 0.89 | TDP1 (0.69) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| Benzyl Benzoate SCHEMBL19206962 | 0.86 | KMT2A (0.74) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27337757 | 0.86 | KMT2A (0.69) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6669062 | 0.85 | RAB9A (0.75) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| Benzyl Benzoate SCHEMBL19206942 | 0.85 | KMT2A (0.82) | MAPTRAB9AALDH1A1TDP1KMT2A | |
| SCHEMBL22388846 | 0.85 | KMT2A (0.76) | MAPTRAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6057219 | 0.85 | KMT2A (0.76) | MAPTRAB9AALDH1A1SMN1; SMN2TDP1 | |
| Benzyl Benzoate SCHEMBL19206952 | 0.85 | TDP1 (0.82) | MAPTRAB9AALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051528-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |