Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669062 | 0.92 | RAB9A (0.75) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL312910 | 0.92 | TDP1 (0.81) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL22388846 | 0.88 | KMT2A (0.76) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL15534582 | 0.87 | RAB9A (0.72) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| Hydrochloric Acid SCHEMBL6333447 | 0.87 | RAB9A (0.60) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL181934 | 0.87 | TDP1 (0.73) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| 4-Methylbenzoic Acid Methyl Ester SCHEMBL7946632 | 0.86 | MAPT (0.64) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL20830625 | 0.86 | TDP1 (0.67) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL3042201 | 0.86 | ALDH1A1 (0.53) | KMT2ATDP1SLC6A2SLC6A3RAB9A | |
| SCHEMBL13469247 | 0.85 | TDP1 (0.71) | KMT2ATDP1SLC6A2SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100475033-C | Cyclopropene supply system | ROHM & HAAS (US) | 2009-04-08 | — | — | CN | disclosed |
| CN-1371603-A | Cyclopropene supply system | ROHM & HAAS (US) | 2002-10-02 | — | — | CN | disclosed |
| CN-1055089-C | Intermediates of protein kinase C inhibitors and preparation process thereof | LILLY CO ELI (US) | 2000-08-02 | — | — | CN | disclosed |
| CN-1050844-C | Protein kinase C inhibitors | LILLY CO ELI (US) | 2000-03-29 | — | — | CN | disclosed |
| CN-1220266-A | Intermediates of protein kinase C inhibitors and preparation process thereof | LILLY CO ELI (US) | 1999-06-23 | — | — | CN | disclosed |
| CN-1111247-A | Protein kinase C inhibitors | LILLY CO ELI (US) | 1995-11-08 | — | — | CN | disclosed |