Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | ACR | P10323 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496824 | 0.83 | MAPK1 (0.55) | SMN1; SMN2TDP1NPC1RAB9AGAA | |
| SCHEMBL7946747 | 0.83 | ELANE (0.49) | SMN1; SMN2TP53HPGDTDP1PRSS1 | |
| SCHEMBL14145709 | 0.80 | AURKA (0.49) | PRSS1ACRTRPV1EPHX2NPC1 | |
| SCHEMBL9578483 | 0.80 | NPC1 (0.51) | SMN1; SMN2TDP1PRSS1ACRNPC1 | |
| SCHEMBL13560798 | 0.80 | AURKA (0.49) | PRSS1ACRTRPV1EPHX2NPC1 | |
| SCHEMBL9061976 | 0.79 | EPHX2 (0.51) | SMN1; SMN2TP53HPGDPRSS1EPHX2 | |
| SCHEMBL14003271 | 0.79 | PRSS1 (0.56) | SMN1; SMN2TP53HPGDTDP1PRSS1 | |
| SCHEMBL12473427 | 0.79 | LMNA (0.60) | SMN1; SMN2PRSS1ACRNPC1RAB9A | |
| SCHEMBL17233760 | 0.79 | CA1 (0.56) | SMN1; SMN2NPC1RAB9AGAAMAPT | |
| SCHEMBL532755 | 0.79 | TP53 (0.47) | SMN1; SMN2TP53HPGDTDP1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258296-B1 | HAS SMALL SPONTANEOUS POLARIZATION AND HAS EXCELLENT RESPONSE CHARACTERISTICS FOR MAKING HIGH QUALITY FERRIELECTRIC LIQUID CRYSTAL DISPLAY DEVICE | MITSUBISHI GAS CHEMICAL COMPANY INC (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-1008585-A1 | FLUORINE-SUBSTITUTED COMPOUNDS AND FERRIELECTRIC LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2000-06-14 | — | — | EP | disclosed |