SCHEMBL7946747

SCHEMBL7946747

CC(=O)Oc1ccc(C(=O)OCC(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.49
HSD17B10 Q99714 1/20 0.47
LMNA P02545 2/20 0.46
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MAPT P10636 2/20 0.43
GAA P10253 1/20 0.43
XBP1 P17861 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
AR P10275 1/20 0.43
CHRM1 P11229 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1496824 0.84 MAPK1 (0.55) ELANELMNAKMT2ASMN1; SMN2NPC1
SCHEMBL18786019 0.84 MAPT (0.44) ELANEHSD17B10LMNAKMT2ASMN1; SMN2
SCHEMBL17233760 0.83 CA1 (0.56) ELANESMN1; SMN2NPC1RAB9AMAPT
SCHEMBL7946740 0.83 SMN1; SMN2 (0.49) HSD17B10SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL13133231 0.81 ELANE (0.56) ELANEHSD17B10LMNAKMT2ASMN1; SMN2
SCHEMBL1176935 0.80 CA12 (0.61) ELANEHSD17B10LMNAKMT2ASMN1; SMN2
SCHEMBL17230480 0.79 KMT2A (0.53) HSD17B10LMNAKMT2ASMN1; SMN2NPC1
SCHEMBL11059672 0.79 PRSS1 (0.62) ELANEHSD17B10LMNAKMT2ASMN1; SMN2
SCHEMBL9446645 0.78 LMNA (0.57) ELANEHSD17B10LMNAKMT2ASMN1; SMN2
SCHEMBL8476252 0.78 ELANE (0.53) ELANEHSD17B10LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220214614-A1 PHOTOACID GENERATORS, PHOTORESIST COMPOSITIONS, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-07-07 US disclosed
US-6258296-B1 HAS SMALL SPONTANEOUS POLARIZATION AND HAS EXCELLENT RESPONSE CHARACTERISTICS FOR MAKING HIGH QUALITY FERRIELECTRIC LIQUID CRYSTAL DISPLAY DEVICE MITSUBISHI GAS CHEMICAL COMPANY INC (JP) 2001-07-10 US disclosed
EP-1008585-A1 FLUORINE-SUBSTITUTED COMPOUNDS AND FERRIELECTRIC LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2000-06-14 EP disclosed