Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13133231 | 0.85 | ELANE (0.56) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL1176935 | 0.84 | CA12 (0.61) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL1243626 | 0.82 | ESR1 (0.50) | LMNAKMT2AMEN1ESR1CHRM1 | |
| SCHEMBL9446645 | 0.82 | LMNA (0.57) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL6704208 | 0.81 | CA1 (0.62) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28798457 | 0.81 | ELANE (0.51) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL9446681 | 0.81 | LMNA (0.56) | ELANELMNAKMT2AMEN1ESR1 | |
| SCHEMBL4644691 | 0.81 | ALDH1A1 (0.64) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL8850878 | 0.81 | ELANE (0.64) | ELANEHSD17B10LMNAKMT2AMEN1 | |
| SCHEMBL9760675 | 0.81 | ELANE (0.64) | ELANEHSD17B10LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981558-A | ANTIMICROBIAL ACTIVITY AND ANTITUMOR ACTIVITY | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0918058-A1 | DC 107 DERIVATIVES (1) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-05-26 | — | — | EP | disclosed |