SCHEMBL7946771

SCHEMBL7946771

CCc1cc2c(cc1C(=O)COC(C)=O)C(C)(C)CCC2(C)C

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RXRA P19793 15/20 0.52
RXRG P48443 7/20 0.49
RXRB P28702 6/20 0.49
RARA P10276 4/20 0.49
RARB P10826 4/20 0.49
RARG P13631 4/20 0.49
HNF4A P41235 2/20 0.40
CXCR2 P25025 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 2/20 0.39
CYP26A1 O43174 1/20 0.39
CYP26B1 Q9NR63 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13479240 0.84 RXRA (0.50) RXRARXRGRXRBRARARARB
SCHEMBL872423 0.80 RXRA (0.61) RXRARXRGRXRBRARARARB
SCHEMBL29395963 0.80 RXRA (0.61) RXRARXRGRXRBRARARARB
SCHEMBL7950320 0.79 RXRA (0.57) RXRARXRGRXRBRARARARB
SCHEMBL13034173 0.79 RXRA (0.47) RXRARXRGRXRBRARARARB
SCHEMBL7217889 0.78 RXRA (0.72) RXRARXRGRXRBRARARARB
Acetic Acid SCHEMBL5879410 0.77 RXRA (0.62) RXRARXRGRXRBRARARARB
SCHEMBL8494220 0.71 RXRA (0.49) RXRARXRGRXRBRARARARB
SCHEMBL2897683 0.70 RXRA (0.64) RXRARXRGRXRBRARARARB
SCHEMBL5540284 0.69 RXRA (0.80) RXRARXRGRXRBRARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6258854-B1 KETONE ETHERS FOR ODORS GIVAUDAN ROURE ( INTERNATIONAL ) SA (CH) 2001-07-10 US disclosed
EP-0983990-A2 Ketones useful as precursors for organoleptic compounds Givaudan Roure (International) S.A. (CH) 2000-03-08 EP disclosed