Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946802 | 0.71 | — | — | |
| SCHEMBL1704445 | 0.68 | TP53 (0.32) | — | |
| SCHEMBL7957603 | 0.68 | — | — | |
| Fluoromethane SCHEMBL27893892 | 0.65 | FAAH (0.39) | CES1 | |
| SCHEMBL152599 | 0.64 | — | — | |
| SCHEMBL7946837 | 0.64 | — | — | |
| SCHEMBL7981132 | 0.63 | — | — | |
| SCHEMBL3195604 | 0.62 | — | — | |
| SCHEMBL23177600 | 0.62 | CES1 (0.34) | CES1 | |
| Ammonia Solution, Strong SCHEMBL30673742 | 0.62 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271403-B1 | PURE ANTIESTROGENS, OR ESTROGENIC ANTIESTROGENS WITH ESTROGENIC PARTIAL ACTION. | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| US-5986115-A | STEROIDS WITH FLUORO GROUPS AND ETHER OR ESTER GROUPS | SCHERING AG (DE) | 1999-11-16 | — | — | US | disclosed |
| US-5866560-A | ESTROGEN INHIBITORS; TUMOR THERAPY; HORMONE REPLACEMENT THERAPY | SCHERING AG (DE) | 1999-02-02 | — | — | US | disclosed |