Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591375 | 0.79 | SLC15A1 (0.43) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7368172 | 0.76 | TAAR1 (0.44) | SLC15A1ALPIPKMPTGS1XIAP | |
| SCHEMBL7357671 | 0.75 | SLC15A1 (0.44) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL11998023 | 0.75 | SLC15A1 (0.44) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL11998010 | 0.75 | SLC15A1 (0.44) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL6580113 | 0.75 | SLC15A1 (0.44) | SLC15A1CSNK1EEPHX1ALPIPKM | |
| SCHEMBL10871667 | 0.74 | EPHX2 (0.45) | SLC15A1CSNK1EEPHX1IDO1ALPI | |
| SCHEMBL7361302 | 0.74 | CYP1A2 (0.47) | SLC15A1SLC6A2SLC6A4LAP3ANPEP | |
| SCHEMBL11998011 | 0.71 | AKR1C3 (0.40) | SLC15A1CSNK1EEPHX1IDO1DPP4 | |
| SCHEMBL7360306 | 0.71 | SLC15A1 (0.47) | MEN1KMT2ASLC15A1CSNK1EALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042892-A1 | PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2010-04-15 | — | — | WO | disclosed |