SCHEMBL7947063

SCHEMBL7947063

OC(F)(F)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2803622 1.00 LMNA (0.35) LMNATHRBF2PRSS1PRSS2
SCHEMBL5386749 1.00 LMNA (0.35) LMNATHRBF2PRSS1PRSS2
SCHEMBL7638924 0.82 LMNA (0.42) LMNATHRBF2PRSS1PRSS2
SCHEMBL7640464 0.81 LMNA (0.33) LMNATHRBF2PRSS1PRSS2
SCHEMBL7638933 0.81 LMNA (0.33) LMNATHRBF2PRSS1PRSS2
SCHEMBL7803333 0.79 THRB (0.32) LMNATHRB
SCHEMBL6256217 0.77 THRB (0.31) LMNATHRB
SCHEMBL6257714 0.77 THRB (0.31) LMNATHRB
SCHEMBL6328126 0.77 LMNA (0.38) LMNATHRB
SCHEMBL3176852 0.77 LMNA (0.38) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001094034-A1 ULTRAHYDROPHOBIC SURFACES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE Technische Universität Dresden (DE) 2001-12-13 WO disclosed