Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HCK | P08631 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.44 |
| ▸ | CASP1 | P29466 | 7/20 | 0.44 |
| ▸ | CASP7 | P55210 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938047 | 0.86 | CYP1A2 (0.56) | MTORPIK3CDABL1EGFRHCK | |
| SCHEMBL7946228 | 0.84 | MTOR (0.48) | MTORKDM5BCYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL7946753 | 0.82 | ALDH1A1 (0.52) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL3223334 | 0.80 | CYP1A2 (0.55) | MTORPIK3CDABL1EGFRHCK | |
| SCHEMBL7945959 | 0.80 | PDE4B (0.51) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL7944623 | 0.79 | ALDH1A1 (0.66) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL7944641 | 0.79 | ALDH1A1 (0.45) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL7944111 | 0.79 | CYP1A2 (0.51) | MTORPIK3CDABL1EGFRHCK | |
| SCHEMBL7949559 | 0.78 | ALDH1A1 (0.49) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 | |
| SCHEMBL7938295 | 0.78 | ALDH1A1 (0.48) | CYP1A2CASP1CASP7HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008775-A1 | AMINOPYRIDOPYRAZINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |