SCHEMBL7947082

SCHEMBL7947082

O=[N+]([O-])c1ccccc1C(OC(c1ccccc1[N+](=O)[O-])[Si](c1ccccc1)(c1ccccc1)c1ccccc1)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.46
ALDH1A1 P00352 7/20 0.45
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 5/20 0.40
HSD17B10 Q99714 2/20 0.38
NPC1 O15118 1/20 0.38
RECQL P46063 1/20 0.38
RAB9A P51151 1/20 0.38
CA1 P00915 3/20 0.37
MAPK1 P28482 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
STAT6 P42226 1/20 0.37
HIF1A Q16665 1/20 0.37
PHLPP2 Q6ZVD8 1/20 0.37
CASP7 P55210 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2777973 0.73 ALDH1A1 (0.54) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL4620107 0.72 ALDH1A1 (0.47) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL4620391 0.72 ALDH1A1 (0.47) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL384635 0.71 CYP1A2 (0.50) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL8521008 0.71 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL31014201 0.71 CYP1A2 (0.58) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL4078018 0.70 CYP1A2 (0.56) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL2821430 0.70 ALDH1A1 (0.51) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL16335086 0.70 CYP1A2 (0.67) CYP1A2ALDH1A1TSHRTDP1HSD17B10
SCHEMBL1116162 0.70 ALDH1A1 (0.56) CYP1A2ALDH1A1TSHRTDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709415-B1 Substrat coated by a base-coat and a clear coat, method of film-forming and coated articles NOF CORP (JP) 2001-07-25 EP disclosed
US-6030571-A Methods of molding and molded articles made thereby NOF CORPORATION (JP) 2000-02-29 US disclosed
US-5922633-A THERMAL LATENT ACID CATALYST CONSISTS OF AN EPOXY COMPOUND, A SULFUR COMPOUND AND LEWIS ACID NOF CORPORATION (JP) 1999-07-13 US disclosed
US-5661219-A AN ACRYLIC COPOLYMER HAVING CARBOXY GROUPS BLOCKED BY A VINYL ETHER, A REACTIVE POLYMER, E.G.HAVING EPOXY GROUPS, AND LEWIS ACID-COMPLEX CATALYST; HIGH SOLIDS; LOW TEMPERATURE CURING; STORAGE STABILITY; MECHANICAL PROPERTIES NOF CORPORATION (JP) 1997-08-26 US disclosed
EP-0643112-B1 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORP (JP) 1997-07-30 EP disclosed
EP-0709415-A2 Curable base-coat composition, method of film-forming and coated articles NOF CORPORATION (JP) 1996-05-01 EP disclosed
EP-0643112-A2 Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article NOF CORPORATION (JP) 1995-03-15 EP disclosed