Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949847 | 0.85 | POLB (0.34) | POLBMAPT | |
| SCHEMBL8407329 | 0.85 | POLB (0.35) | POLBMAPT | |
| SCHEMBL7938353 | 0.82 | POLB (0.34) | POLBMAPT | |
| SCHEMBL9273347 | 0.82 | POLB (0.34) | POLBMAPT | |
| SCHEMBL7938354 | 0.82 | POLB (0.36) | POLBMAPT | |
| SCHEMBL7944854 | 0.80 | POLB (0.33) | POLBMAPT | |
| SCHEMBL7947170 | 0.80 | POLB (0.33) | POLBMAPT | |
| SCHEMBL7946072 | 0.80 | POLB (0.33) | POLBMAPT | |
| SCHEMBL8410110 | 0.80 | PGR (0.36) | POLBMAPT | |
| SCHEMBL5891966 | 0.80 | PGR (0.36) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258803-B1 | 11-ETHYL-17-HYDROXY-19-NORPREGN-4-EN-20-YN-3-ONE FOR MENOPAUSE TREATMENT | AKZO NOBEL N.V. (NL) | 2001-07-10 | — | — | US | disclosed |
| US-6037339-A | METHOD FOR TREATING OSTEOPOROSIS | AKZO NOBEL N.V. (NL) | 2000-03-14 | — | — | US | disclosed |
| US-5710144-A | OSTEOPOROSIS | AKZO NOBEL N.V. (NL) | 1998-01-20 | — | — | US | disclosed |