Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535134 | 0.89 | POLB (0.35) | POLBMAPTESR1ARESR2 | |
| SCHEMBL7938353 | 0.87 | POLB (0.34) | POLBMAPT | |
| SCHEMBL9273347 | 0.87 | POLB (0.34) | POLBMAPT | |
| SCHEMBL7949847 | 0.85 | POLB (0.34) | POLBMAPTESR1ARESR2 | |
| SCHEMBL7944854 | 0.85 | POLB (0.33) | POLBMAPT | |
| SCHEMBL8410110 | 0.85 | PGR (0.36) | POLBMAPTAR | |
| SCHEMBL5891966 | 0.85 | PGR (0.36) | POLBMAPTAR | |
| SCHEMBL7938354 | 0.85 | POLB (0.36) | POLBMAPT | |
| SCHEMBL7947165 | 0.85 | POLB (0.34) | POLBMAPT | |
| SCHEMBL7947160 | 0.84 | POLB (0.32) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643070-B1 | Steroid intermediates and process for their preparation | JENAPHARM GMBH (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5831104-A | Steroid intermediate products and method of their production | JENAPHARM GMBH (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0643070-A1 | Steroid intermediates and process for their preparation | JENAPHARM GmbH (DE) | 1995-03-15 | — | — | EP | disclosed |