Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938354 | 0.91 | POLB (0.36) | POLBMAPT | |
| SCHEMBL7946072 | 0.89 | POLB (0.33) | POLBMAPT | |
| SCHEMBL7947170 | 0.89 | POLB (0.33) | POLBMAPT | |
| SCHEMBL7947160 | 0.88 | POLB (0.32) | POLBMAPT | |
| SCHEMBL8407329 | 0.85 | POLB (0.35) | POLBMAPTARESR1ESR2 | |
| SCHEMBL7947165 | 0.85 | POLB (0.34) | POLBMAPT | |
| SCHEMBL9273347 | 0.83 | POLB (0.34) | POLBMAPT | |
| SCHEMBL7938353 | 0.83 | POLB (0.34) | POLBMAPT | |
| SCHEMBL8407179 | 0.81 | PGR (0.36) | POLBMAPTAR | |
| SCHEMBL7944854 | 0.81 | POLB (0.33) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258803-B1 | 11-ETHYL-17-HYDROXY-19-NORPREGN-4-EN-20-YN-3-ONE FOR MENOPAUSE TREATMENT | AKZO NOBEL N.V. (NL) | 2001-07-10 | — | — | US | disclosed |
| US-6037339-A | METHOD FOR TREATING OSTEOPOROSIS | AKZO NOBEL N.V. (NL) | 2000-03-14 | — | — | US | disclosed |
| US-5710144-A | OSTEOPOROSIS | AKZO NOBEL N.V. (NL) | 1998-01-20 | — | — | US | disclosed |