Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992897 | 0.90 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL7001262 | 0.89 | MEN1 (0.57) | MEN1KMT2AKDM4ESIGMAR1ACHE | |
| SCHEMBL7961148 | 0.89 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL6996711 | 0.87 | ACHE (0.46) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL7985035 | 0.85 | ACHE (0.46) | MEN1KMT2AKDM4ESIGMAR1ACHE | |
| SCHEMBL7956635 | 0.82 | KDM4E (0.42) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL27406398 | 0.80 | MEN1 (0.50) | MEN1KMT2AMAPTKDM4ESIGMAR1 | |
| SCHEMBL27404097 | 0.78 | ACHE (0.44) | MEN1KMT2ASMN1; SMN2LMNAKDM4E | |
| SCHEMBL16874556 | 0.77 | SIGMAR1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTLMNA | |
| SCHEMBL16874555 | 0.77 | SIGMAR1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |