Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946627 | 0.95 | KMT2A (0.59) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7947590 | 0.91 | ALDH1A1 (0.65) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7945542 | 0.87 | ALDH1A1 (0.67) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7950537 | 0.81 | POLB (0.50) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL6816341 | 0.81 | ALDH1A1 (0.63) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7938939 | 0.79 | MAPT (0.56) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7945458 | 0.78 | MAPT (0.48) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL7939128 | 0.76 | LMNA (0.52) | KMT2AALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7939040 | 0.76 | NPC1 (0.56) | KMT2AALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL6814937 | 0.75 | ALDH1A1 (0.72) | KMT2AALDH1A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |