Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7939052 | 0.90 | ALDH1A1 (0.49) | LMNASMN1; SMN2ALDH1A1PYGLCYP1A2 | |
| SCHEMBL7945458 | 0.83 | MAPT (0.48) | LMNASMN1; SMN2ALDH1A1PYGLCYP1A2 | |
| SCHEMBL7950537 | 0.83 | POLB (0.50) | LMNASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL7939140 | 0.81 | KMT2A (0.43) | LMNASMN1; SMN2ALDH1A1CYP3A4MAPT | |
| SCHEMBL7945326 | 0.80 | KMT2A (0.41) | LMNASMN1; SMN2ALDH1A1PYGLMAPT | |
| SCHEMBL7947343 | 0.76 | KMT2A (0.57) | LMNASMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL7946708 | 0.76 | MAPT (0.45) | LMNASMN1; SMN2PYGLMAPTNPC1 | |
| SCHEMBL7950802 | 0.76 | ALDH1A1 (0.54) | LMNASMN1; SMN2ALDH1A1PYGLCYP3A4 | |
| SCHEMBL7947590 | 0.74 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1PYGLCYP1A2CYP3A4 | |
| SCHEMBL7947441 | 0.74 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2ALDH1A1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |