SCHEMBL7947368

SCHEMBL7947368

C#CCN[C@]1(I)CCc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.41
MAOA P21397 4/20 0.41
BCHE P06276 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
ACHE P22303 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR6 P50406 1/20 0.38
KDM1A O60341 4/20 0.38
SIGMAR1 Q99720 5/20 0.35
HDAC9 Q9UKV0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7341859 0.78 MAOB (0.38) MAOBMAOABCHEADRA2BADRA2C
SCHEMBL5807645 0.78 KDM1A (0.40) MAOBMAOABCHEADRA2BADRA2C
SCHEMBL4348712 0.78 MAOB (0.38) MAOBMAOABCHEADRA2BADRA2C
SCHEMBL6277987 0.73 MAOB (0.34) MAOBMAOABCHEADRA2BADRA2C
SCHEMBL1051970 0.71 MAOB (0.39) MAOBMAOABCHEADRA2BADRA2C
SCHEMBL16192661 0.69 HDAC9 (0.35) MAOBMAOASIGMAR1HDAC9ALDH1A1
SCHEMBL27967814 0.69 KDM1A (0.39) MAOBMAOAKDM1ASIGMAR1ALDH1A1
SCHEMBL14860973 0.69 KDM1A (0.38) MAOBMAOABCHEADRA2BADRA2C
Hydrochloric Acid SCHEMBL3783562 0.68 KDM1A (0.35) MAOBMAOAKDM1ASIGMAR1HDAC9
SCHEMBL24129618 0.66 KDM1A (0.46) MAOBKDM1ASIGMAR1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010007181-A2 NEW SALT FORMS OF AN AMINOINDAN DERIVATIVE MEDICHEM, S.A. (ES) 2010-01-21 WO disclosed
WO-2009141737-A2 A NEW METHOD FOR OBTAINING AN AMINOINDAN MESYLATE DERIVATIVE MEDICHEM, S.A. (ES) 2009-11-26 WO disclosed