Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844831 | 0.84 | TPMT (0.46) | HTR3EGMNNHTR3BCYP1A2CYP2D6 | |
| SCHEMBL31647047 | 0.77 | TP53 (0.40) | HTR3EGMNNHTR3BCYP1A2CYP2D6 | |
| SCHEMBL31646442 | 0.77 | NOTUM (0.41) | HTR3EGMNNHTR3BCYP1A2CYP2D6 | |
| SCHEMBL31646897 | 0.76 | STAT3 (0.34) | HTR3EGMNNHTR3BCYP1A2CYP2D6 | |
| SCHEMBL8955378 | 0.75 | TPMT (0.61) | ALOX15TSHRHSD17B10ALDH1A1POLB | |
| SCHEMBL7058435 | 0.74 | CA12 (0.47) | ALOX15TSHRHSD17B10STAT3ALDH1A1 | |
| SCHEMBL3688381 | 0.74 | ALDH1A1 (0.55) | ALOX15TSHRHSD17B10ALDH1A1POLB | |
| SCHEMBL6811311 | 0.74 | SLC13A3 (0.40) | TSHRALDH1A1CA12CA1CA9 | |
| SCHEMBL31646838 | 0.72 | SMN1; SMN2 (0.44) | ALDH1A1GAAMEN1KMT2ANR1H4 | |
| SCHEMBL1424585 | 0.72 | KMT2A (0.34) | STAT3ALDH1A1TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255349-B1 | PREVENTION REPRODUCTION; VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-03 | — | — | US | disclosed |