Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 2/20 | 0.61 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5177578 | 0.85 | ALDH1A1 (0.61) | TPMTHCAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL680955 | 0.85 | ALDH1A1 (0.61) | TPMTHCAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL69625 | 0.78 | TPMT (0.89) | TPMTHCAR1ALDH1A1KDM4EHCAR2 | |
| SCHEMBL28214359 | 0.78 | TPMT (1.00) | TPMTHCAR1ALDH1A1KDM4EHCAR2 | |
| SCHEMBL23699 | 0.78 | TPMT (1.00) | TPMTHCAR1ALDH1A1KDM4EHCAR2 | |
| SCHEMBL14292553 | 0.78 | TPMT (0.64) | TPMTHCAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL10345223 | 0.78 | CA12 (0.60) | TPMTHCAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL12260650 | 0.76 | ALDH1A1 (0.52) | TPMTHCAR1ALDH1A1KDM4EMEN1 | |
| SCHEMBL2898633 | 0.76 | ALDH1A1 (0.52) | TPMTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7947374 | 0.75 | HTR3E (0.35) | TPMTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516805-A | 3,5-substituted aminobenzoylguanidines, their use as a medicament or diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-14 | — | — | US | disclosed |