Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816561 | 0.84 | KMT2A (0.47) | KDM4EKMT2AMEN1SHMT2ALDH1A1 | |
| SCHEMBL7947455 | 0.80 | KMT2A (0.46) | KDM4EKMT2AMEN1GRIK1ALDH1A1 | |
| SCHEMBL6819238 | 0.69 | SHMT2 (0.47) | KDM4EKMT2AMEN1SHMT2ALDH1A1 | |
| SCHEMBL28286023 | 0.67 | KDM4E (0.45) | KDM4EKMT2AMEN1ALDH1A1ATM | |
| SCHEMBL6816378 | 0.66 | KMT2A (0.69) | KDM4EKMT2AMEN1SHMT2ALDH1A1 | |
| SCHEMBL6814951 | 0.65 | ALDH1A1 (0.46) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6810995 | 0.65 | KDM4E (0.50) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6811904 | 0.65 | KMT2A (0.47) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6814780 | 0.65 | KDM4E (0.50) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6815995 | 0.65 | KMT2A (0.47) | KDM4EKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |