Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947460 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL6816557 | 0.83 | MAPT (0.56) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL7947456 | 0.80 | KDM4E (0.43) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL28286023 | 0.69 | KDM4E (0.45) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL6819231 | 0.68 | MAPT (0.63) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL535326 | 0.67 | PLK1 (0.65) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6816565 | 0.66 | MAPT (0.60) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL6816369 | 0.65 | KMT2A (0.79) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL7134009 | 0.65 | ALDH1A1 (0.68) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL6880369 | 0.65 | CDC25B (0.59) | KMT2AMEN1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |