Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947455 | 0.84 | KMT2A (0.46) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL6816565 | 0.81 | MAPT (0.60) | ALDH1A1KMT2AGAALMNAMAPT | |
| SCHEMBL11007347 | 0.67 | ALDH1A1 (0.72) | ALDH1A1KMT2AGAALMNARAB9A | |
| SCHEMBL6819231 | 0.67 | MAPT (0.63) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL30362713 | 0.66 | ALDH1A1 (0.82) | ALDH1A1KMT2AGAALMNARAB9A | |
| SCHEMBL28401841 | 0.66 | ALDH1A1 (0.82) | ALDH1A1KMT2AGAALMNARAB9A | |
| SCHEMBL6816557 | 0.66 | MAPT (0.56) | ALDH1A1KMT2ALMNAMAPTHPGD | |
| SCHEMBL5450034 | 0.64 | GAA (0.76) | ALDH1A1KMT2AGAALMNARAB9A | |
| SCHEMBL11309072 | 0.64 | LCLAT1 (0.36) | ALDH1A1KMT2AGAALMNAMAPT | |
| Chlorobenzene SCHEMBL8843354 | 0.63 | IDO1 (0.79) | ALDH1A1KMT2AIDO1EP300KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |