Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.54 |
| ▸ | TACR1 | P25103 | 18/20 | 0.54 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956540 | 0.84 | CCR5 (0.58) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL8296291 | 0.77 | TACR1 (0.63) | TACR1TACR2TACR3 | |
| SCHEMBL7847578 | 0.75 | TACR1 (0.61) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL8347309 | 0.75 | TACR1 (0.68) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL7765748 | 0.75 | CCR5 (0.41) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL8807992 | 0.74 | CCR5 (0.41) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL7956549 | 0.73 | TACR1 (0.49) | CCR5TACR1 | |
| SCHEMBL8351334 | 0.73 | TACR1 (0.66) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL8808253 | 0.73 | CCR5 (0.44) | CCR5TACR1TACR2TACR3 | |
| SCHEMBL8811706 | 0.73 | CCR5 (0.42) | CCR5TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |