Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.61 |
| ▸ | LIPE | Q05469 | 7/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 2/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956524 | 0.84 | LIPG (0.60) | LIPGLIPESCN3AHSD11B1HRH3 | |
| SCHEMBL7961497 | 0.84 | LIPG (0.60) | LIPGLIPESCN3AHSD11B1HRH3 | |
| SCHEMBL7956252 | 0.84 | LIPG (0.60) | LIPGLIPESCN3AHSD11B1HRH3 | |
| SCHEMBL7947575 | 0.81 | LIPG (0.57) | LIPGLIPEHSD11B1HRH3SCD | |
| SCHEMBL7961541 | 0.79 | LIPG (0.53) | LIPGLIPEHSD11B1HRH3 | |
| SCHEMBL23702850 | 0.79 | LIPG (0.62) | LIPGLIPEHSD11B1LPLHRH3 | |
| SCHEMBL23708114 | 0.79 | LIPG (0.62) | LIPGLIPEHSD11B1LPLHRH3 | |
| SCHEMBL23708112 | 0.79 | LIPG (0.65) | LIPGLIPEHSD11B1LPLHRH3 | |
| SCHEMBL23708498 | 0.79 | LIPG (0.65) | LIPGLIPEHSD11B1LPLHRH3 | |
| SCHEMBL23703427 | 0.79 | LIPG (0.62) | LIPGLIPEHSD11B1LPLHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313127-B1 | FOR THERAPY OF HYPERCHOLESTEROLEMIA OR ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |