Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7947674 | 0.90 | SMN1; SMN2 (0.53) | MAPTLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL5733357 | 0.90 | KDM4E (0.63) | PTPN1LMNANPC1RAB9AKDM4E | |
| SCHEMBL7957043 | 0.84 | USP2 (0.64) | KDM4EKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL15028195 | 0.82 | TTR (0.60) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5734066 | 0.81 | MAPT (0.55) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7957021 | 0.81 | KDM4E (0.58) | PTPN1LMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL7962009 | 0.80 | KDM4E (0.60) | PTPN1LMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL7961594 | 0.79 | MAPT (0.59) | MAPTLMNATP53SMN1; SMN2NPC1 | |
| SCHEMBL3742473 | 0.78 | KMO (0.51) | PTPN1MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL15028365 | 0.77 | USP2 (0.54) | MAPTLMNATP53SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |